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NF-B-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

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At the cellular level, the authors showed that the presence of Pt NPs significantly reduced the levels of hypoxia-inducible factors, indicating their ability to improve the hypoxic environment (Figures 4G,H)

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Compared to peptide GLP- 1 receptor agonists, orforglipron, exhibits less receptor desensitization by increasing cyclic AMP signaling [105]