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Therefore, ferroptosis of NK cells leads to insufficient anti-tumor immune function, which prevents the elimination and inhibition of tumor cells in a timely manner and helps tumor cells evade immune surveillance

Conclusions and perspectives By integrating mechanistic insights and disease-specific evidence, this review delineated how ATFs orchestrate macrophage development, survival, migration, phagocytosis, activation, cytokine secretion and polarization and how these regulatory axes converge to shape macrophage-driven pathology in infectious, inflammatory, metabolic, oncologic and neurodegenerative settings

[DOI] [PubMed] [Google Scholar] Tilley BC, Palesch YY, Kieburtz K, Ravina B, Huang P, Elm JJ, Shannon K, Wooten GF, Tanner CM, Goetz GC, Investigators N-P, 2006

The K av values were plotted as a function of the logMW and fitted using a linear equation

Collagen is only part of the story, says Dr