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In contrast, HGN exhibited reduced antioxidant enzyme activities, decreased proline and soluble sugar levels, and a marked increase in malondialdehyde content, reflecting greater lipid peroxidation and cellular damage (Fig

Cobbett, University of Melbourne), ggt4 and pcs1pcs2 (Erwin Grill, Technische Universitt Mnchen), ggt1 (Dongtao Ren, China Agricultural University), nrc1 and nrc2 (Julian Schroeder, University of California San Diego), zir1 (Kuo-Chen Yeh, Academia Sinica)

doi: 10.1038/sj.ejcn.1602300 8 AquilanoK.BaldelliS.CirioloM

Among these elements, ATF3 predominantly regulates the basal and stress-induced expression of ChaC1 through ATF/CRE, while ATF4 primarily regulates stress-induced ChaC1 expression through ATF/CRE and ACM (48)

GSH and N-acetylcysteine (NAC) have proven antioxidant and neuroprotective properties