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Experimental & Molecular Medicine

AS-IV induces the expression of the epithelial cell marker E-cadherin to be upregulated and that of renal mesenchymal cell markers to be downregulated

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Other genes implicated in PD pathogenesis, such as UCHL1, GBA, VPS35 , and ATP13A2 (177, 178), also have established roles in influencing mitochondrial function and integrity