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Notably, 8-hydroxy-2-deoxyguanosine (8-OHdG), a marker of oxidative DNA damage, is elevated in liver biopsy specimens of MASLD patients, and 31 P-MRS imaging has demonstrated ATP depletion consistent with mitochondrial dysfunction [101, 102]

The recent development indeed extends its application to their use as transporters with genome-editing tools at the CRISPR-Cas9 component level of resolution [26]

A study comparing individuals with insomnia to healthy sleepers found significantly lower glutathione peroxidase activity in the insomnia group

For example, DMOCPTL regulates EGR1 in TNBC cells and induces GPX4 ubiquitination to reduce EGR4 protein levels, thereby regulating mitochondria-mediated apoptosis [80]

L-carnitine is known for its role in supporting muscle strength, normal fat metabolism, and healthy energy production