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Expert Revi Respir Med 15:9931002 Ibrahim M, Vegel A, Niu A, Panse K, Chen R, Safah H, Socola F, Luk A, Saba NS (2021) Reinfection versus failure of viral clearance in a COVID-19 patient with hematologic malignancy

Yes, certain medications can interfere with the absorption or effectiveness of Cyanocobalamin

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This includes upregulation of antioxidant enzymes (superoxide dismutase, catalase) that protect against oxidative damage, enhancement of growth factor expression (TGF-, VEGF, PDGF) that supports tissue repair, and suppression of inflammatory gene expression that contributes to chronic skin degradation