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Aryl Bis (diazeniumdiolates): Potent Inducers of S -Glutathionylation of Cellular Proteins and Their in Vitro Antiproliferative Activities

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Oxidative stress produces multiple pathological products, such as Superoxide Dismutase (SOD), Malondialdehyde (MDA), etc., which cause damage to cellular macromolecules and most importantly, mutations in genomic DNA (Wang et al., 2018

matsudana leaf tissues using Trizol reagent (Invitrogen, USA) following the manufacturers protocol, and the quantity was measured with the Nano Drop UV-VIS 2000 spectrophotometer (Thermo Fisher Scientific, Waltham, MA, USA)

Spheroids were grown under standard tissue culture conditions in an incubator (37 C and 5% CO 2 )