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These results suggest that L-carnitine supplementation could prevent lenvatinib-induced muscle toxicity without diminishing its antineoplastic activity, although further clinical studies are needed to validate these findings

It was made as reported 33 using phenol red-free DMEM/F12 medium, containing 7% CSS, penicillin (100 U/ml), streptomycin (100 U/ml), diluted GlutaMAX 100X (Gibco), 10 mM Hepes, B27 supplement (50 stock solution