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doi: 10.1007/s00394-014-0706-z

In one trial examining 45 HIV-positive men and women, taking 800 mg daily for four months, NAC was successful in normalizing plasma cysteine levels and significantly reducing TNF-a, but there were no changes in glutathione levels

Ingredients: 10 mg Vitamin C (as ascorbic acid), 10 mcg Vitamin D3 (as cholecalciferol), 10 mg NADH (reduced nicotinamide adenine dinucleotide), 50 mg Glutathione (as L-Glutathione), 3 mg CoEnzyme Q10 (as Ubiquinone), 5 mg NAC (N-acetyl-L-cysteine), 2 mg Curcumin, 1 mg Quercetin (as Quercetin dihydrate), 1 mg Alpha-Lipoic Acid), pressure-sensitive adhesive

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Conclusion: Altogether, our results show that the cellular antioxidant defense systems contribute to leukemia resistance to MTX, and targeting these pathways, especially the thioredoxin antioxidant system, may be a promising strategy for resensitizing ALL to MTX