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In addition, PGA and Kyn/Trp may have potential as biomarkers for disease monitoring and risk stratification, although their clinical utility will require validation in independent and longitudinal cohorts

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Studies show that PUFA-phospholipids (PUFA-PLs) are phospholipids that are most likely to undergo peroxidation reactions (Gaschler and Stockwell, 2017), especially phosphatidylethanolamine (PE)-containing phospholipids with arachidonic acid (AA) and adrenic acid (AdA)

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