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Keep Limber, Keep Fit Many knee problems are caused by tight or imbalanced musculature

Abnormal stress signaling has been noted in patients with fibromyalgia and other chronic pain disorders

On the other hand, at low levels, cadaverine is imported to the cytoplasm of macrophages by L-lysine transporters, inducing a modest increase in glycolysis that supports Oxphos and itaconate generation

Finally, translational progress is bottlenecked by the lack of strategies to selectively manipulate p53s ferroptosis-regulating activity: activating its pro-ferroptotic function in cancer cells while preserving its anti-ferroptotic role in normal tissues remains a major challenge, and no validated biomarkers exist to predict which tumors will respond to p53-targeted ferroptosis therapies

Jo SK, Lee WY, Rhee EJ, Won JC, Jung CH, Park CY, Oh KW, Park SW, Kim SW