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Description

The Spectrum of Mutations of Homocystinuria in the MENA Region

Calcium homeostasis dysregulation impacts A aggregation, tau hyperphosphorylation, synaptic damage, neuronal apoptosis, mitochondrial dysfunction, oxidative stress, and neuroinflammation [69,70,71,72,73,74,75]

Proc Natl Acad Sci (2006) 103(20):760712

Misgeld and Schwarz, 2017)

Moreover, Tyr 6 , Trp 7 and Leu 12 of GST were shown to interact with glutathione [16], and our results show that F1 peptide G YW KIKG L V contains Tyr 6 , Trp 7 and Leu 12 (indicated in bold letters)