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Topical agents like retinoids, vitamin E can be used but there is little evidence supporting their benefits in this phase ( Chronic ulceration Removal of the necrotic tissue and employing advanced therapies like skin substitutes, growth factors, and hyperbaric oxygen may be beneficial for non-healing ulcers ( Hyperpigmentation/telangiectasia For vascular lesions or telangiectasia (these are small visible blood vessels that appears on skin

Additionally, it is worth noting that the current study focused on the various groups of antioxidant molecules, including pigments, polysaccharides, peptides, phycobiliproteins, mycosporine-like amino acids, phenolics, and alkaloids, from these phyla

Beyond intestinal soapbile acids in metabolic control

In particular, miRNAs are well-known regulators of adhesion, invasion, metastatic process [6] and recently, emerging evidence supports their role in the regulation of cancer metabolism

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