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Data availability Nucleotide sequences of codon-optimized genes can be found in Supplementary Table 6

FIGURE 5 Hongyan et al

Prior to the analysis, G422 cells were seeded at a density of 1 10 6 cells/well in a 12-well plate and allowed to adhere and proliferate overnight under optimal culture conditions

To enhance efficacy, a 2025 randomized controlled trial compared rifaximin monotherapy with a combination of rifaximin and a multi-strain probiotic (150)