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Moreover, a recent randomized crossover study in healthy women demonstrated that prolonged mild sleep restriction markedly increased endothelial oxidative stress without activating compensatory antioxidant responses, due to reduced expression of DCUN1D3 gene, a regulator of the Nrf2-mediated antioxidant pathway, thereby suggesting a mechanistic link between insufficient sleep and vascular oxidative injury 78

doi: 10.1515/jbcpp-2018-0150 312 Heydari NasrabadiMTajabadi EbrahimiMDehghan BanadakiSHKajousangiTZahediF

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CaM plays a role in maintaining Ca 2+ balance which can be disrupted when NAPQI binds to mitochondrial proteins (Ray et al

These tests can also help rule out other possible causes of facial weakness that may need addressing, such as Guillain-Barr syndrome or Lyme disease