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10.1186/1756-8722-3-43 189 XiaY.TianH.YinZ.JiangC.LiuZ.ZhangH.et al (2025)

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In particular, Eadesgroup in 2011 identified and validated for the first time in MDA-MB-231 and Hs578T breast cancer cells a miRNA, miR-200a, able to target the KEAP1 3-untranslated region (3-UTR), leading to KEAP1 mRNA degradation and, consequently, NRF2 stabilization and translocation to the nucleus [178]