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Patients may be diagnosed with pernicious anaemia , a condition where the deficiency is due to the lack of intrinsic factor a protein necessary for vitamin B12 absorption

If take-back programs are not available, the FDA recommends mixing the medication with an unpalatable substance such as coffee grounds or cat litter, sealing it in a container, and disposing of it in household trash after removing or obscuring personal information on the prescription label

Due to the nonconsenting nature of future children as stakeholders, a specialized ethical evaluation is required to evaluate the adequacy of consent mechanisms in representing their interests

In 149 pediatric patients aged 12 years to 17 years the most frequently reported adverse reactions (at least 2%) were headache (8%), abdominal pain (3%), diarrhea (2%), and nausea (2%)