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There's a really interesting paper by Arnall et al

Our second set of simulations used the enzyme concentrations obtained above, and instead varied substrate concentrations to model different conditions

Although discovered several decades ago, studies continue to identify pro-inflammatory roles for leptin and anti-inflammatory activities for adiponectin, hormones secreted in large amounts by the adipocyte

doi: 10.2174/156720501205150526114000 55 DhillonK

This study thus broadens the conceptual framework of neutrophil immunometabolism and proposes targeting the Chac2GSH axis as a potential therapeutic strategy for systemic comorbidities associated with periodontitis