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It has also been demonstrated that the long non-coding RNA PWAR6, which is overexpressed in metastatic colorectal cancer tissues, functions as a competitive inhibitor of Keap1, thereby promoting the stabilization of NRF2

Oxidative stress causes endothelial dysfunction The endothelium-derived relaxing factor, previously identified as NO 28 or a closely related compound, 29 has potent anti-atherosclerotic properties