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GABA A receptors are heteropentamers composed of various subunits such as , , , , , , , and (Figures 2A,B), which are found throughout the brain (Fritschy and Mohler, 1995), including regions involved in alcohol-related use such as the prefrontal cortex, thalamus, cerebellum, or the amygdala (Bowery et al., 1987)

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