[18] The glyoxalase system, consisting of glyoxalase I and II, uses glutathione to convert the reactive dicarbonyl methylglyoxal, a by-product of glycolysis, into Dlactate
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Nrf2 acts as a vital in vivo antioxidant protector, with research indicating that Nrf2 pathway activation safeguards retinal tissue in patients with diabetes (359, 360)
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