selenium benefits glutathione peroxidase The role of metabolism and selenoproteins in cartilage homeostasis and arthropathies Selenium and Selenoproteins: Mechanisms, Health

3.2 Amino acid metabolism As early as the 1950s and 1960s, Harry Eagle observed a form of cell death similar to ferroptosis, which he described as amino acid-dependent cell death (Eagle, 1955)

HGF promotes angiogenesis and neurogenesis, potentially improving nerve regeneration

To accommodate the tumors growth, there is an upregulation in the expression of angiogenic factors like vascular endothelial growth factor (VEGF), leading to the abnormal proliferation and expansion of tumor vasculature, a hallmark of high-grade gliomas [145]

While N6F11 has shown some cell-specific properties, it requires higher concentrations to achieve effectiveness compared to well-known non-selective ferroptosis activators [36]

NIR-light-controlled G-quadruplex hydrogel for synergistically enhancing photodynamic therapy via sustained delivery of metformin and catalase-like activity in breast cancer