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Description

Role of CYP2A5 and 2G1 in acetaminophen metabolism and toxicity in the olfactory mucosa of the Cyp1a2(/) Mouse

Oncology 35, 2225

While these agents often spare normal proliferating tissues, they introduce new toxicity patternssuch as dermatologic reactions, QT prolongation, diarrhea, and hepatotoxicityoften linked to the pathways they target in normal tissues