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IV access, pump rate control, and emergency response capacity are typical reasons IV NAD+ is administered in licensed clinic settings rather than home research-use settings

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As noted, a significant subset of ED patients (~30% or more) do not respond fully to PDE5is

Only reads that uniquely mapped to the reference sequence chr17: 34,283,17334,286,052 of the Homo sapiens genome (Gencode, release 38) were considered for the methylation analysis