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Open-source and reduced-expenditure nanosystem with ROS self-amplification and glutathione depletion for simultaneous augmented chemodynamic/photodynamic therapy

The only thrombolytic medication that has received FDA approval is tissue fibrinogen activator (tPA), but its clinical application is restricted to a certain time window (Fukuta et al., 2017

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For the HCA, plated cells were given fluorescent labels which allowed both morphological assessment (such as cell area and diameter, membrane permeability and mitochondrial activity) and cell segmentation for the consequent analysis