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60 While these studies indicate a positive influence of lipids on the functionality and metabolism of CD8 + T cells in the TME, it is important to note that alterations to T-cell lipid metabolism might attenuate their antitumoral effects

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Additionally, Lin et al

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However, the associated costs in design complexity and manufacturing sensitivity position it as a specialized, high-performance tool, to be prioritized when precision-driven translational mandates surpass operational simplicity or cost-efficiency considerations