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In PFR+GzmB-induced pyroptosis, Cys180 is also essential for GzmB recognition and the resultant pyroptosis (Supplementary Fig

2019), though the literature is still very much scarce in this regard

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Hemoglobin Heme next moves into the cytosol where it is linked to the heme pocket of globin in a precise and stable position that permits binding of oxygen to the heme