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Accetta D, Syverson G, Bonacci B, Reddy S, Bengtson C, Surfus J, et al

doi: 10.1016/j.ccell.2016.04.012 59 GuiX.YangH.LiT.TanX.ShiP.LiM.et al

Dilda, Tumour Metabolism Group, Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia e-mail: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology

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Specifically, the neurofilament light chain (NfL), a cytoskeletal structural protein of myelinated axons that is detectable in both CSF and serum after neuronal injury, has demonstrated potential in delirium as a prognostic and diagnostic CNS-derived biomarker [86, 88,89,90,91,92]