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Description

This triggers the Mitochondrial Antiviral Signaling (MAVS) pathway, locking the immune system into a state of chronic, hyperactive inflammation that continually damages surrounding tissues

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1 Baker J, Hardy MP, Zhou J, Bondy C, Lupu F, Bellve AR, Efstratiadis A: Effects of an Igf1 gene null mutation on mouse reproduction

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However, the development of AOD-9604 as an anti-obesity pill was terminated in 2007 for lack of effectiveness in trials [1]

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