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Conclusion: Our study findings provide a comprehensive metabolomic knowledge base and other soluble biomarkers for a better understanding of the pathophysiology of LC and suggests sarcosine and serine supplementations might have potential therapeutic implications in LC patients

doi: 10.3389/fendo.2024.1466775 Received 18 July 2024 Accepted 15 November 2024 Published 10 December 2024 Volume 15 - 2024 Edited by ke Sjholm, Gvle Hospital, Sweden Reviewed by Zhen Geng, Shanghai University, China Sanjiv Neupane, Stony Brook University, United States Updates Copyright 2024 Jia, Zhang and Yu

Mouse Model For Studying The Efficiency Ofgenetic Vaccines In Transfecting Human Muscle Cells And Inducing Human Immune Responses In Vivo There is a lack of suitable in vivo models for studies of the efficiency of genetic vaccines and the vast majority of studies are performed on the mouse model, in which it is sometimes difficult to predict whether the results obtained reliably predict similar vaccinations in humans because of the complexity of events occurring after genetic vaccination A lack of suitable in vivo models has hampered studies of the efficiency of genetic vaccines in inducing antigen expression in human muscle cells and in inducing specific human immune responses

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Alcohol can increase hypoglycemia risk, particularly for patients with diabetes taking additional glucose-lowering medications like insulin or sulfonylureas