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Currently, dozens of mRNA-based vaccines, anti-cancer agents, and gene therapies are undergoing clinical trials [1,2,3]

Amongst these mutations, 182 (83.9%) are single nucleotide substitutions, 19 (8.7%) are multiple nucleotide substitutions, 11 (5.1%) are deletions, and 5 (2.3%) are intronic mutations

All crystals were flash frozen in a liquid nitrogen stream at 100 K after a quick soaking in their mother liquor supplemented with 20% glycerol

doi: 10.1071/RD9950659 79 KodamaHKuribayashiYGagnonC

The ligandin function of GSTs Because of exhibiting a ligand binding function, glutathione tranferases, have been known as ligandin, a function, which involves the noncovalent binding of nonsubstrate hydrophobic ligands such as heme, bilirubin, various steroids, and conceivably some lipophilic anticancer drugs as well