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Physical stamina often improves, too, so a flight of stairs or an afternoon walk may feel less draining

Therapeutic strategies targeting glutamine metabolismsuch as the antagonist DON, combined with glycolytic inhibitor 2-DG or metformincan suppress effector T cell responses, though the effects of glutamate supplementation may vary depending on the pathological context, necessitating tailored approaches (120, 121)

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People with Vitamin B12 deficiency may notice: In some cases, the pigmentation may gradually improve after Vitamin B12 levels are restored through treatment