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Thus, although we cannot exclude off-target effects, our data suggest that p300/SIRT2 pathway may contribute to the regulation of G6PD activity during IV infection and suggest G6PD as a potential target to control the redox cell environment in virus-infected cells

Lynch et al., 2021

In this context, the peptidase, DJ-1 could have a prominent role because it possess reactive cysteines and is a modulator of mitochondrial dynamics and mitophagy ( FIGURE 2 Apoptosis and ATG are processes altered in cancer cells that show critical metabolic transformations associated with enhanced cellular stress

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Randomized, double-blind, pilot evaluation of intravenous glutathione in Parkinsons disease