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For example, its serves as a cellular substrate to the hepatitis C virus NS3-4A protease (28), and ectopic expression of GPX8 in the rat pancreatic -cells induces ER stress (29)

38 In PD and HD, pro-apoptotic proteins such as BCL2-associated X (BAX)and p53 upregulated modulator of apoptosis (PUMA) are upregulated, while anti-apoptotic factors like B-cell lymphoma 2 (BCL-2) are downregulated, tipping the balance toward cell death

Injuries to the PCL can be graded as I, II or III depending on the severity of the injury

These nozzle-containing bands were harvested, dialyzed against Tris buffer, and either directly analyzed or further purified as described above for the cyanobacteria

Fang Y, Su Y, Xu J, Hu Z, Zhao K, Liu C, et al