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At the transcriptional level, this treatment coincides with the modulated expression of genes encoding chromatin remodeling complexes (e.g., SWI/SNF, SNF2) and transcription factors (e.g., WRKY, NAC, bZIP)

Neither is approved for general research or veterinary use

This article describes 67 patients who developed hepatic injury after ingestion of acetaminophen for therapeutic reasons

Higher doses can stall the same process or even tip into toxicity over longer exposures, where free copper drifting loose from the complex starts driving oxidative damage

Binds and inhibits aldose reductase gene to exert its anti-cataract activity: an in vitro mechanistic study