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The APN exerts its biological functions through ligand-receptor interactions with two transmembrane receptors, APN Receptor 1 (AdipoR1) and AdipoR2

Nuytinck, L

Studies also showed that genetic deletion of Rieske iron-sulfur protein (RISP, complex III cofactor) in PASMCs counteracts hypoxia-induced increase in mitochondrial ROS and cytoplasmic calcium (Guzy et al., 2005

doi: 10.3390/ijms18040774 76 FujiharaYAbeTAsawaYNishizawaSSaijoHHikitaAet al

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