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In the future, in-depth analysis of the molecular mechanisms by which it induces gut microbiota dysbiosis (such as LPS release, activation of inflammatory signaling pathways, etc.) may offer a significant theoretical basis to support the development of OA therapeutic

Metabotropic glutamate receptors at the aged mossy fiber - CA3 synapse of the hippocampus

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The obtained AuNPs-d-PLL were further modified with SH-PEG 5000 -OCH 3 (Mw 5400 g.mol -1 ) or SH-PEG 5000 -FA as confirmed by DLS and Zeta potential measurements