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10.1016/j.phymed.2020.153218 328 SahaS.PanigrahiD

5.2.4 Polyphenol oxidases (PPOs) PPOs are omnipresent Cu-containing enzymes which utilize molecular Oxygen for catalytic hydroxylation and dehydrogenation of o- diphenolic compounds like catechol and caffeic acid to their respective quinones, which leads to the alkylation of nucleophilic groups and self-polymerization to produce dark-coloured melanin polymers [185]

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NOD represents a subgroup of patients that encompass all recent diagnoses of diabetes that include T1D, T2D, and T3cD ( Figure 2 )

Enhancing B12 Intake Through Diet In addition to supplements, elderly individuals should be encouraged to consume foods rich in vitamin B12