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Increased expression of PHGDH and prognostic significance in colorectal cancer

In contrast, deletion or inhibition of GPX4 causes rapid H 2 O 2 accumulation and RIPK3-mediated necrosome activation 72,73

Feedback control by insulin of liver glutathione-insulin transhydrogenase in rat

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For example, decreased sodium excretion (increasing levels) results in water retention and a condition known as volume overload, which causes swelling of tissues (edema)