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Amino acids may regulate the mTOR pathway or autophagic proteins which are essential for the fusion of secretory vesicles to form the ruffled border and resorb bone (DeSelm et al, 2011)

Histological analysis further confirmed substantial improvement in tendon healing quality after 2 weeks of treatment ( Despite its therapeutic potential, rhIGF-1 encounters several clinical limitations, primarily due to its structural homology with insulin, which may lead to hypoglycemia and growth hormone (GH) suppression ( in vivo half-life and susceptibility to proteolytic degradation