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Nature 509 , 439446 (2014)

[2] A few small studies and case reports have suggested that biotin supplementation might thicken or strengthen brittle nails in some individuals, but these studies often lack placebo control and involve oral biotin, not injections

NBs originate from neural crest cells and typically form in the abdominal or thoracic regions in paraspinal ganglia ( MYCN is a transcription factor belonging to the highly homologous MYC -family of cellular oncogenes, ubiquitously expressed in mammals

B Vitamins work so closely with one another that a deficiency in any one B Vitamin can lead to poor functioning of any or all of the others even if they are in good supply

What preventive measures must be taken for safe administration