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Relative abundance of each phylum or genus was calculated in each sample by dividing the abundance of the respective phylum or genus by the sum of the abundances of all phyla or genera for that sample, then multiplying by 100 to generate a percentage

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FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes