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In agreement with the decrease in TEER and increase in BBB paracellular permeability, tight junction proteins and adherens junction protein, -catenin, expression and localization are also altered with LPS treatment [71]

When they get too short, the cell can no longer replicate

Dihexa restored spatial learning and memory in rats with chemically induced cognitive impairment

After 7d of selection, the cells were used in their respective assays

Data from preclinical studies is promising but more human trials will need to be conducted to determine the full extent of KPV's abilities, as well as its safety and dosing parameters