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Kohsaka S, Takahashi K, Wang L, Tanino M, Kimura T, Nishihara H et al

For example, CMS may use the internet or other sources to perform an environmental scan of the geographic area of the country in which the requesting hospital is located or intends to expand, identify trends, recent events, or planned events (such as expected population growth or new employers entering the local market), or review information related to the quality of care at the requesting hospital and other hospitals in its community

Zhang W, Zhou B, Yang X, Zhao J, Hu J, Ding Y

Research suggests higher amounts might be safe too [1]

(2007) Mycothiol import by Mycobacterium smegmatis and function as a resource for metabolic precursors and energy production