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doi: 10.1182/blood-2009-12-260083 102 LiuXWangTWangWLiangXMuYXuYet al

In streptozotocin-induced diabetic rats, there was decreased transketolase expression and activity in renal glomeruli, liver, skeletal muscle and RBCs after 12 weeks of diabetes was found associated with progressive increase in the renal clearance of thiamine and increased albuminuria with duration of diabetes, suggesting that abnormal renal handling of thiamine may occur early in the process of impairment of renal function in diabetes [190]

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2011 Oct;49(8):755-9

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