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Abbreviations AFP: Alpha-fetoprotein ATM: Ataxia telangiectasia mutated ATRA: All-trans retinoic acid BCR: Biochemical recurrence b-FGF: b-fibroblast growth factor C/EBP: CCAAT/enhancer-binding protein cdc25A: Cell division cycle 25A CMM: Cutaneous malignant melanoma ECM: Extracellular matrix ECs: Endothelial cells EHMT1: Euchromatin histone methyltransferase 1 ELFEMFs: Extremely low-frequency electromagnetic fields ER: Estrogen receptor FADD: Fas-associated death domain GIF: Growth inhibitory factor HIF-1: Hypoxia-inducible factor-1 IL: Interleukin KO: Knockout LOH: Loss of heterozygosity MCM-2: Minichromosome maintenance protein 2 MMP: Matrix metalloproteinase MTs: Metallothioneins NCBI: National Center of Biotechnology Information NF-B: Nuclear factor-B NPs: Nanoparticles PDGF: Platelet-derived growth factor PI3K: Phosphatidylinositol 3-kinase pRNA: Packaging RNA rPOA: Reducible poly(oligo-d-arginine) shMT: Short hairpin RNAs against MTs siRNA: Short interfering RNA SMCs: Smooth muscle cells SNP: Single nucleotide polymorphism TGCTs: Testicular germ cell tumors TGF1: Transforming growth factor 1 TNM: Tumor node metastasis tPSA: Total prostate-specific antigen VEGF: Vascular endothelial growth factor References Coyle P, Philcox JC, Carey LC, Rofe AM

Another study published titled Men with high levels of anabolic hormones less likely to develop worsening frailty Proved that having higher baseline levels of vitamin D, insulin-like growth factor-1 (IGF-1), and its binding protein 3 (IGFBP3) was associated with a lower risk of worse frailty status four years later [2]

Zhao 6 , 129 patients) suggest cell therapy improves motor scores at 1224 months