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Remarkably, GSH depletion significantly decreased the expression of these key fibrogenic factors under both chow and HFD conditions (Figure 3, A and B)

The molecular mechanisms and signaling pathways underlying these benefits are complex and multifaceted, encompassing direct interactions with gut microbiota, strengthening of gut barrier function, modulation of immune responses, and attenuation of systemic inflammation

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a , b , Quantification of NETs in WT and XKR8-deficient BMNs or HL-60 cells treated with PMA (100 nM) in the presence of inhibitors listed in Fig

MACS is still treatable with the same strategies and targeted treatments Dr