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72 These findings suggest that subnormal ALP levels may be a useful diagnostic tool for HPP, that PLP levels may be useful in patients with a suspected diagnosis of HPP, for screening family members to detect possible heterozygotes, and to monitor response to therapy

(2005) 81:230S42S

Eighteen years later, FDAs briefing document for its December 2024 advisory committee meeting put the same event into the regulatory record with more clinical detail