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(PubMed) Rude RK, Shils ME

This analysis, which encompassed 10 cohort studies with a total of 182,202 middle-aged subjects and approximately 8,500 cases of extrahepatic cancers at different sites over a median follow-up of 5.8 years, revealed that MASLD increases the risk of thyroid cancer by approximately 2.5-fold

Additionally, IGF-1 modulates mitochondrial metabolism, enhances glucose uptake, and increases the availability of glutamate transporters, preventing excitotoxicity [1012]