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IP was induced by daily oral administration (3 g/g weight) of MTX using a feeding needle (Thermo Fisher Scientific, Waltham, MA), as indicated in Table 2

Aging Cell 11 , 542552 (2012)

Thiostrepton (TST, purity ~99%), RSL3 (purity ~99%), and ferrostatin-1 (Fer-1, purity ~99%) were purchased from MedChemExpress (MCE, USA) and dissolved in dimethyl sulfoxide (DMSO)

Wang H, Sama AE

In this review, we summarize the current existing literatures on NADPH metabolism, including its biological functions, regulatory mechanisms, and the corresponding therapeutic interventions directly or indirectly targeting NADPH metabolism in cancer